科學60秒:非洲人也可能患瘧疾
來源：滬江聽寫酷
2011-07-17 10:00
A new development in malaria:
“Plasmodium vivax, the world’s most common malaria parasite, now infects people previously considered to be ____1____.”
Peter Zimmerman from Case Western Reserve University school of medicine spoke at the AAAS meeting in Washington on February 19th.
“So, red blood cells of most African people do not ____2____ the Duffy blood-group protein. Now, the Duffy blood-group protein is ____3____ for Plasmodium vivax to get into the red cell. Duffy-negative Africans have been considered to be resistant to Plasmodium vivax.”
Zimmerman studied Malagasy populations on Madagascar. He found that 10 percent of Duffy-negative subjects were in fact ____4____ Plasmodium vivax.
“So we’ve shown that Plasmodium vivax has cleared Duffy negativity. If Plasmodium vivax is evolving to learn how to infect the Duffy-negative red cell, then a large continent of people suddenly ____5____ a new form of malaria.”
【視聽版科學小組榮譽出品】
“Plasmodium vivax, the world’s most common malaria parasite, now infects people previously considered to be ____1____.”
Peter Zimmerman from Case Western Reserve University school of medicine spoke at the AAAS meeting in Washington on February 19th.
“So, red blood cells of most African people do not ____2____ the Duffy blood-group protein. Now, the Duffy blood-group protein is ____3____ for Plasmodium vivax to get into the red cell. Duffy-negative Africans have been considered to be resistant to Plasmodium vivax.”
Zimmerman studied Malagasy populations on Madagascar. He found that 10 percent of Duffy-negative subjects were in fact ____4____ Plasmodium vivax.
“So we’ve shown that Plasmodium vivax has cleared Duffy negativity. If Plasmodium vivax is evolving to learn how to infect the Duffy-negative red cell, then a large continent of people suddenly ____5____ a new form of malaria.”
【視聽版科學小組榮譽出品】
resistant
express
essentially necessary
infected with
becomes susceptible to
瘧疾的最新研究進展：
“間日瘧原蟲是世上最常見的瘧疾寄生蟲，現(xiàn)在，這種寄生蟲也會感染那些之前被認為抗瘧疾病的人?！?在2月19日，來自凱斯西儲大學醫(yī)學院的皮特?齊默曼于華盛頓在美國科學發(fā)展協(xié)會會議中發(fā)表講話?！耙虼?，大部分非洲人的紅細胞不會表達達菲蛋白?，F(xiàn)在間日瘧原蟲必須依靠達菲蛋白進入紅細胞。不表達達菲蛋白的非洲人曾被認為是不會感染間日瘧原蟲的?！?齊默曼研究了馬達加斯加上土地上的馬達加斯加人。他發(fā)現(xiàn)10%沒有達菲蛋白的人實際上都被間日瘧原蟲感染了。因此我們證明了不表達達菲蛋白的人已經不再能抵抗間日瘧原蟲了。如果間日瘧原蟲進化到可以影響不表達達菲蛋白的紅細胞，那么突然之間，這片大陸上就會有很多人可能患上了一種新的虐疾病。
