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Tech Team Puts Microscope on Cell Phone

After hundreds of years, the most common, basic microscopes still operate by means of the same old hardware: the lens. But what if you could do away with that lens and create a microscope that fits on a cell phone? That’s what researchers led by Aydogan Ozcan at U.C.L.A. have developed. Ozcan recently won an NSF (National Science Foundation) Early Career Development award for his work.

幾百年來最普通最常見的顯微鏡使用的仍然是最古老的硬件:透鏡??赡隳懿荒軖伒敉哥R,發(fā)明適用于手機的顯微鏡呢?加州大學(xué)洛杉磯分校由艾多安?歐茲坎帶頭的研究者們就是這么做的。由于這項工作,歐茲坎最近贏得了美國國家科學(xué)基金會杰出青年研究獎。

Normal microscopes image cells themselves. But Ozcan’s team is imaging their shadows. Tissue cells and bacteria are semi-transparent—light penetrating through cells causes shadings and reveals texture. Ozcan uses an LED as his light source, creating cellular shadows. An algorithm turns those shadows into an image of the cells.

普通顯微鏡本身就會為細(xì)胞成像,但歐茲坎的小組考慮的則是用它的陰影。組織細(xì)胞及細(xì)菌是半透明的,透過細(xì)胞的光會制造陰影并反映出其結(jié)構(gòu)。歐茲坎用LED(發(fā)光二極管)作為光源,以此制造細(xì)胞的陰影。某種算法則將這些陰影變?yōu)榧?xì)胞的影像。

Millions of people in the developing world suffer because they’re misdiagnosed, or because simple diseases are missed. With this system, a blood sample can be loaded into a small imaging device attached to a cell phone. The cellular image generated from the sample can be transmitted to a central computer in a nearby hospital. The image can be assessed for disease, with the resulting diagnosis sent back to the field in just minutes. Tests of the device begin in Africa this summer.

發(fā)展中國家有數(shù)以百萬計的人忍受著痛苦,僅僅因為誤診或醫(yī)生漏掉了簡單的疾病。有了這個系統(tǒng),血樣可以上傳到與手機相連的小型成像裝置上,血樣產(chǎn)生的細(xì)胞影像可以傳往附近醫(yī)院的中央計算機上,影像可用來判斷疾病,診斷結(jié)果幾分鐘之內(nèi)就可傳回現(xiàn)場。今年夏天非洲已經(jīng)開始測試這項裝置。

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